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Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate-resistance and novel therapeutic approaches

Prostate cancer is the second-leading cause of cancer-related mortality in men in Western societies. Androgen receptor (AR) signaling is a critical survival pathway for prostate cancer cells, and androgen-deprivation therapy (ADT) remains the principal treatment for patients with locally advanced an...

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Autori principali: Karantanos, Theodoros, Corn, Paul G., Thompson, Timothy C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908870/
https://ncbi.nlm.nih.gov/pubmed/23752182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.206
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