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GEMMs shine a light on resistance to androgen deprivation therapy for prostate cancer

Androgen deprivation therapy (ADT) for advanced prostate cancer inexorably leads to resistance, and clinically useful biomarkers are lacking. The value of genetically engineered mice for co-clinical studies is clearly demonstrated in a recent publication that reveals XAF1, XIAP, and SRD5A1 as novel...

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Detalhes bibliográficos
Main Authors: Karantanos, Theodoros, Thompson, Timothy C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881957/
https://ncbi.nlm.nih.gov/pubmed/23845440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2013.06.007
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