Suppression of Autophagic Flux by Bile Acids in Hepatocytes

Retention of bile acids (BAs) in the liver during cholestasis plays an important role in the development of cholestatic liver injury. Several studies have reported that high concentrations of certain BAs induce cell death and inflammatory response in the liver, and BAs may promote liver tumorigenesi...

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Main Authors: Manley, Sharon, Ni, Hong-Min, Kong, Bo, Apte, Udayan, Guo, Grace, Ding, Wen-Xing
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908720/
https://ncbi.nlm.nih.gov/pubmed/24189133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft246
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