Differential Roles of Unsaturated and Saturated Fatty Acids on Autophagy and Apoptosis in Hepatocytes

Fatty acid-induced lipotoxicity plays a critical role in the pathogenesis of nonalcoholic liver disease. Saturated fatty acids and unsaturated fatty acids have differential effects on cell death and steatosis, but the mechanisms responsible for these differences are not known. Using cultured HepG2 c...

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Autors principals: Mei, Shuang, Ni, Hong-Min, Manley, Sharon, Bockus, Abigail, Kassel, Karen M., Luyendyk, James P., Copple, Bryan L., Ding, Wen-Xing
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2011
Matèries:
Cellular and Molecular
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199993/
https://ncbi.nlm.nih.gov/pubmed/21856859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.184341
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