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A clinical evaluation tool for SNP arrays, especially for autosomal recessive conditions in offspring of consanguineous parents

PURPOSE: This report describes a fast online tool to accelerate and improve clinical interpretation of single nucleotide polymorphism array results for diagnostic purposes, when consanguinity or inbreeding is identified. METHODS: We developed a web-based program that permits entry of regions of homo...

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Detalhes bibliográficos
Main Authors: Wierenga, Klaas J., Jiang, Zhijie, Yang, Amy C., Mulvihill, John J., Tsinoremas, Nicholas F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908554/
https://ncbi.nlm.nih.gov/pubmed/23100014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gim.2012.136
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