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UBE4B Protein Couples Ubiquitination and Sorting Machineries to Enable Epidermal Growth Factor Receptor (EGFR) Degradation

The signaling of plasma membrane proteins is tuned by internalization and sorting in the endocytic pathway prior to recycling or degradation in lysosomes. Ubiquitin modification allows recognition and association of cargo with endosomally associated protein complexes, enabling sorting of proteins to...

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Main Authors: Sirisaengtaksin, Natalie, Gireud, Monica, Yan, Qing, Kubota, Yoshihisa, Meza, Denisse, Waymire, Jack C., Zage, Peter E., Bean, Andrew J.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908433/
https://ncbi.nlm.nih.gov/pubmed/24344129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.495671
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