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Pannexin 3 Inhibits Proliferation of Osteoprogenitor Cells by Regulating Wnt and p21 Signaling

Canonical Wnt signaling and BMP promote the proliferation and differentiation of osteoprogenitors, respectively. However, the regulatory mechanism involved in the transition from proliferation to differentiation is unclear. Here, we show that Panx3 (pannexin 3) plays a key role in this transition by...

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Bibliographische Detailangaben
Hauptverfasser: Ishikawa, Masaki, Iwamoto, Tsutomu, Fukumoto, Satoshi, Yamada, Yoshihiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908416/
https://ncbi.nlm.nih.gov/pubmed/24338011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.523241
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