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Pannexin 3 and connexin 43 modulate skeletal development through their distinct functions and expression patterns

Pannexin 3 (Panx3) and connexin 43 (Cx43; also known as GJA1) are two major gap junction proteins expressed in osteoblasts. Here, we studied their functional relationships in skeletal formation by generating Panx3(−/−) and Panx3(−/−);Cx43(−/−) mice and comparing their skeletal phenotypes with Cx43(−...

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Bibliografiske detaljer
Udgivet i:J Cell Sci
Main Authors: Ishikawa, Masaki, Williams, Geneva L., Ikeuchi, Tomoko, Sakai, Kiyoshi, Fukumoto, Satoshi, Yamada, Yoshihiko
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813316/
https://ncbi.nlm.nih.gov/pubmed/26759176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.176883
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