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Pannexin 3 Inhibits Proliferation of Osteoprogenitor Cells by Regulating Wnt and p21 Signaling

Canonical Wnt signaling and BMP promote the proliferation and differentiation of osteoprogenitors, respectively. However, the regulatory mechanism involved in the transition from proliferation to differentiation is unclear. Here, we show that Panx3 (pannexin 3) plays a key role in this transition by...

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Bibliografiske detaljer
Main Authors: Ishikawa, Masaki, Iwamoto, Tsutomu, Fukumoto, Satoshi, Yamada, Yoshihiko
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908416/
https://ncbi.nlm.nih.gov/pubmed/24338011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.523241
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