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Pannexin 3 Inhibits Proliferation of Osteoprogenitor Cells by Regulating Wnt and p21 Signaling

Canonical Wnt signaling and BMP promote the proliferation and differentiation of osteoprogenitors, respectively. However, the regulatory mechanism involved in the transition from proliferation to differentiation is unclear. Here, we show that Panx3 (pannexin 3) plays a key role in this transition by...

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Detalhes bibliográficos
Main Authors: Ishikawa, Masaki, Iwamoto, Tsutomu, Fukumoto, Satoshi, Yamada, Yoshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908416/
https://ncbi.nlm.nih.gov/pubmed/24338011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.523241
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