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Intracellular and Extracellular Carbonic Anhydrases Cooperate Non-enzymatically to Enhance Activity of Monocarboxylate Transporters

Proton-coupled monocarboxylate transporters (MCTs) are carriers of high-energy metabolites such as lactate, pyruvate, and ketone bodies and are expressed in most tissues. It has previously been shown that transport activity of MCT1 and MCT4 is enhanced by the cytosolic carbonic anhydrase II (CAII) i...

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Bibliografiske detaljer
Main Authors: Klier, Michael, Andes, Fabian T., Deitmer, Joachim W., Becker, Holger M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908409/
https://ncbi.nlm.nih.gov/pubmed/24338019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537043
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