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Intracellular and Extracellular Carbonic Anhydrases Cooperate Non-enzymatically to Enhance Activity of Monocarboxylate Transporters

Proton-coupled monocarboxylate transporters (MCTs) are carriers of high-energy metabolites such as lactate, pyruvate, and ketone bodies and are expressed in most tissues. It has previously been shown that transport activity of MCT1 and MCT4 is enhanced by the cytosolic carbonic anhydrase II (CAII) i...

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Main Authors: Klier, Michael, Andes, Fabian T., Deitmer, Joachim W., Becker, Holger M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908409/
https://ncbi.nlm.nih.gov/pubmed/24338019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537043
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