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Loss of oncogenic ras expression does not correlate with loss of tumorigenicity in human cells.

ras oncogenes are mutated in at variety of human tumors, which suggests that they play an important role in human carcinogenesis. To determine whether continued oncogenic ras expression is necessary to maintain the malignant phenotype, we studied the human fibrosarcoma cell line, HT1080, which conta...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Plattner, R, Anderson, M J, Sato, K Y, Fasching, C L, Der, C J, Stanbridge, E J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39083/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692875/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6665
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