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Loss of oncogenic ras expression does not correlate with loss of tumorigenicity in human cells.

ras oncogenes are mutated in at variety of human tumors, which suggests that they play an important role in human carcinogenesis. To determine whether continued oncogenic ras expression is necessary to maintain the malignant phenotype, we studied the human fibrosarcoma cell line, HT1080, which conta...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Plattner, R, Anderson, M J, Sato, K Y, Fasching, C L, Der, C J, Stanbridge, E J
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1996
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39083/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692875/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6665
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