Loss of oncogenic ras expression does not correlate with loss of tumorigenicity in human cells.

ras oncogenes are mutated in at variety of human tumors, which suggests that they play an important role in human carcinogenesis. To determine whether continued oncogenic ras expression is necessary to maintain the malignant phenotype, we studied the human fibrosarcoma cell line, HT1080, which conta...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Plattner, R, Anderson, M J, Sato, K Y, Fasching, C L, Der, C J, Stanbridge, E J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39083/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692875/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6665
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