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Growth differentiating factor 15 enhances the tumor-initiating and self-renewal potential of multiple myeloma cells

Disease relapse remains a major factor limiting the survival of cancer patients. In the plasma cell malignancy multiple myeloma (MM), nearly all patients ultimately succumb to disease relapse and progression despite new therapies that have improved remission rates. Tumor regrowth indicates that clon...

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Autori principali: Tanno, Toshihiko, Lim, Yiting, Wang, Qiuju, Chesi, Marta, Bergsagel, P. Leif, Matthews, Geoff, Johnstone, Ricky W., Ghosh, Nilanjan, Borrello, Ivan, Huff, Carol Ann, Matsui, William
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907757/
https://ncbi.nlm.nih.gov/pubmed/24345755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-08-524025
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