TDP-43 Inclusion Bodies Formed in Bacteria Are Structurally Amorphous, Non-Amyloid and Inherently Toxic to Neuroblastoma Cells

Accumulation of ubiquitin-positive, tau- and α-synuclein-negative intracellular inclusions of TDP-43 in the central nervous system represents the major hallmark correlated to amyotrophic lateral sclerosis and frontotemporal lobar degeneration with ubiquitin-positive inclusions. Such inclusions have...

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Détails bibliographiques
Auteurs principaux: Capitini, Claudia, Conti, Simona, Perni, Michele, Guidi, Francesca, Cascella, Roberta, De Poli, Angela, Penco, Amanda, Relini, Annalisa, Cecchi, Cristina, Chiti, Fabrizio
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907574/
https://ncbi.nlm.nih.gov/pubmed/24497973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086720
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