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Parasite-Antigen Driven Expansion of IL-5(−) and IL-5(+) Th2 Human Subpopulations in Lymphatic Filariasis and Their Differential Dependence on IL-10 and TGFβ
BACKGROUND: Two different Th2 subsets have been defined recently on the basis of IL-5 expression – an IL-5(+)Th2 subset and an IL-5(−)Th2 subset in the setting of allergy. However, the role of these newly described CD4(+) T cells subpopulations has not been explored in other contexts. METHODS: To st...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3907332/ https://ncbi.nlm.nih.gov/pubmed/24498448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002658 |
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