Expansion of Parasite-Specific CD4(+) and CD8(+) T Cells Expressing IL-10 Superfamily Cytokine Members and Their Regulation in Human Lymphatic Filariasis

BACKGROUND: Lymphatic filariasis (LF) is known to be associated with an increased production of IL-10. The role of the other IL-10 family members in the pathogenesis of infection and/or disease is not known. METHODOLOGY/PRINCIPAL FINDINGS: We examined the expression patterns of IL-10 family members...

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Detalhes bibliográficos
Main Authors: Anuradha, Rajamanickam, George, Parakkal Jovvian, Hanna, Luke E., Kumaran, Paul, Chandrasekaran, Vedachalam, Nutman, Thomas B., Babu, Subash
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974669/
https://ncbi.nlm.nih.gov/pubmed/24699268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002762
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