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Parasite-Antigen Driven Expansion of IL-5(−) and IL-5(+) Th2 Human Subpopulations in Lymphatic Filariasis and Their Differential Dependence on IL-10 and TGFβ

BACKGROUND: Two different Th2 subsets have been defined recently on the basis of IL-5 expression – an IL-5(+)Th2 subset and an IL-5(−)Th2 subset in the setting of allergy. However, the role of these newly described CD4(+) T cells subpopulations has not been explored in other contexts. METHODS: To st...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Anuradha, Rajamanickam, George, Parakkal Jovvian, Hanna, Luke E., Chandrasekaran, Vedachalam, Kumaran, P. Paul, Nutman, Thomas B., Babu, Subash
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907332/
https://ncbi.nlm.nih.gov/pubmed/24498448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002658
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