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Protein kinase D2 induces invasion of pancreatic cancer cells by regulating matrix metalloproteinases

Pancreatic cancer cell invasion, metastasis, and angiogenesis are major challenges for the development of novel therapeutic strategies. Protein kinase D (PKD) isoforms are involved in controlling tumor cell motility, angiogenesis, and metastasis. In particular PKD2 expression is up-regulated in panc...

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Detalhes bibliográficos
Main Authors: Wille, Christoph, Köhler, Conny, Armacki, Milena, Jamali, Arsia, Gössele, Ulrike, Pfizenmaier, Klaus, Seufferlein, Thomas, Eiseler, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907273/
https://ncbi.nlm.nih.gov/pubmed/24336522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-06-0334
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