Protein Kinase D1 Mediates Anchorage-dependent and -independent Growth of Tumor Cells via the Zinc Finger Transcription Factor Snail1

We here identify protein kinase D1 (PKD1) as a major regulator of anchorage-dependent and -independent growth of cancer cells controlled via the transcription factor Snail1. Using FRET, we demonstrate that PKD1, but not PKD2, efficiently interacts with Snail1 in nuclei. PKD1 phosphorylates Snail1 at...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Eiseler, Tim, Köhler, Conny, Nimmagadda, Subbaiah Chary, Jamali, Arsia, Funk, Nancy, Joodi, Golsa, Storz, Peter, Seufferlein, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463335/
https://ncbi.nlm.nih.gov/pubmed/22791710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.370999
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados