The Autodepalmitoylating Activity of APT Maintains the Spatial Organization of Palmitoylated Membrane Proteins

The localization and signaling of S-palmitoylated peripheral membrane proteins is sustained by an acylation cycle in which acyl protein thioesterases (APTs) depalmitoylate mislocalized palmitoylated proteins on endomembranes. However, the APTs are themselves reversibly S-palmitoylated, which localiz...

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Bibliografiske detaljer
Main Authors: Vartak, Nachiket, Papke, Bjoern, Grecco, Hernan E., Rossmannek, Lisaweta, Waldmann, Herbert, Hedberg, Christian, Bastiaens, Philippe I.H.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2014
Fag:
Cell Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907232/
https://ncbi.nlm.nih.gov/pubmed/24411241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.11.024
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