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Clofarabine plus Low-Dose Cytarabine Followed by Clofarabine plus Low-Dose Cytarabine Alternating with Decitabine in AML Frontline Therapy of Older Patients

BACKGROUND: Standard therapy for older patients with AML has a poor outcome. We have designed a combination of clofarabine plus low-dose cytarabine followed by a prolonged consolidation alternating with decitabine. METHODS: Sixty patients with a median age of 70 years (range 60-81) with newly diagno...

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Main Authors: Faderl, Stefan, Ravandi, Farhad, Huang, Xuelin, Wang, Xuemei, Jabbour, Elias, Garcia-Manero, Guillermo, Kadia, Tapan, Ferrajoli, Alessandra, Konopleva, Marina, Borthakur, Gautam, Burger, Jan, Feliu, Jennie, Kantarjian, Hagop M.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907176/
https://ncbi.nlm.nih.gov/pubmed/22282348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27429
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