Final Results of a Phase II Trial of Clofarabine and Low-Dose Cytarabine Alternating with Decitabine in Older Patients with Newly Diagnosed Acute Myeloid Leukemia

BACKGROUND: Treatment of older adults with acute myeloid leukemia (AML) using standard, intensive chemotherapy has been associated with poor outcomes. Effective, less toxic therapies are needed to achieve and maintain durable remissions. METHODS: One-hundred eighteen patients with a median age of 68...

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Veröffentlicht in:Cancer
Hauptverfasser: Kadia, Tapan M., Faderl, Stefan, Ravandi, Farhad, Jabbour, Elias, Garcia-Manero, Guillermo, Borthakur, Gautam, Ferrajoli, Alessandra, Konopleva, Marina, Burger, Jan, Huang, Xuelin, Wang, Xuemei, Pierce, Sherry, Brandt, Mark, Feliu, Jennie, Cortes, Jorge, Kantarjian, Hagop
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436272/
https://ncbi.nlm.nih.gov/pubmed/25809968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.29367
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