A randomized study of clofarabine versus clofarabine plus low-dose cytarabine as front-line therapy for patients aged 60 years and older with acute myeloid leukemia and high-risk myelodysplastic syndrome

We previously reported the feasibility of clofarabine and cytarabine combinations in AML. Questions remain as to (1) the therapeutic advantage of this combination and (2) the role of lower doses of clofarabine and cytarabine in older patients. We have conducted an adaptively randomized study of lowe...

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Detalhes bibliográficos
Main Authors: Faderl, Stefan, Ravandi, Farhad, Huang, Xuelin, Garcia-Manero, Guillermo, Ferrajoli, Alessandra, Estrov, Zeev, Borthakur, Gautam, Verstovsek, Srdan, Thomas, Deborah A., Kwari, Monica, Kantarjian, Hagop M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081352/
https://ncbi.nlm.nih.gov/pubmed/18565853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-124602
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