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Nucleolar GTPase NOG-1 Regulates Development, Fat Storage, and Longevity through Insulin/IGF Signaling in C. elegans

NOG1 is a nucleolar GTPase that is critical for 60S ribosome biogenesis. Recently, NOG1 was identified as one of the downstream regulators of target of rapamycin (TOR) in yeast. It is reported that TOR is involved in regulating lifespan and fat storage in Caenorhabditis elegans. Here, we show that t...

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Hlavní autoři: Kim, Young-Il, Bandyopadhyay, Jaya, Cho, Injeong, Lee, Juyeon, Park, Dae Ho, Cho, Jeong Hoon
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Molecular and Cellular Biology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907010/
https://ncbi.nlm.nih.gov/pubmed/24552710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2014.2251
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