Analgesic tolerance of opioid agonists in mutant mu-opioid receptors expressed in sensory neurons following intrathecal plasmid gene delivery

BACKGROUND: Phosphorylation sites in the C-terminus of mu-opioid receptors (MORs) are known to play critical roles in the receptor functions. Our understanding of their participation in opioid analgesia is mostly based on studies of opioid effects on mutant receptors expressed in in vitro preparatio...

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Bibliografiske detaljer
Main Authors: Li, Guangwen, Ma, Fei, Gu, Yanping, Huang, Li-Yen Mae
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906983/
https://ncbi.nlm.nih.gov/pubmed/24304623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-9-63
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