Analgesic tolerance to microinjection of the μ-opioid agonist DAMGO into the ventrolateral periaqueductal gray

Repeated administration of the relatively low-efficacy μ-opioid receptor agonist morphine induces tolerance to its antinociceptive effects. High-efficacy agonists such as D-Ala2NMePhe4,Gly-ol5 (DAMGO) have been shown to be less effective at producing tolerance, suggesting that different neural mecha...

Full description

Saved in:

Bibliographic Details
Main Authors:	Meyer, Paul J., Fossum, Erin N., Ingram, Susan L., Morgan, Michael M.
Format:	Artigo
Language:	Inglês
Published:	2007
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1971241/ https://ncbi.nlm.nih.gov/pubmed/17445843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2007.03.002
Tags:	Add Tag No Tags, Be the first to tag this record!

Analgesic tolerance to microinjection of the μ-opioid agonist DAMGO into the ventrolateral periaqueductal gray

Similar Items