Telomerase Activity-Independent Function of TERT Allows Glioma Cells to Attain Cancer Stem Cell Characteristics by Inducing EGFR Expression

Telomerase reverse transcriptase (TERT), the catalytic subunit of the enzyme telomerase, is robustly expressed in cancer cells. TERT enables cells to avoid chromosome shortening during repeated replication by maintaining telomere length. However, several lines of evidence indicate that many cancer c...

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Autors principals: Beck, Samuel, Jin, Xun, Sohn, Young-Woo, Kim, Jun-Kyum, Kim, Sung-Hak, Yin, Jinlong, Pian, Xumin, Kim, Sung-Chan, Nam, Do-Hyun, Choi, Yun-Jaie, Kim, Hyunggee
Format: Artigo
Idioma:Inglês
Publicat: Korea Society for Molecular and Cellular Biology 2011
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906874/
https://ncbi.nlm.nih.gov/pubmed/21193962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-011-0008-8
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