Telomerase Activity-Independent Function of TERT Allows Glioma Cells to Attain Cancer Stem Cell Characteristics by Inducing EGFR Expression

Telomerase reverse transcriptase (TERT), the catalytic subunit of the enzyme telomerase, is robustly expressed in cancer cells. TERT enables cells to avoid chromosome shortening during repeated replication by maintaining telomere length. However, several lines of evidence indicate that many cancer c...

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Détails bibliographiques
Auteurs principaux: Beck, Samuel, Jin, Xun, Sohn, Young-Woo, Kim, Jun-Kyum, Kim, Sung-Hak, Yin, Jinlong, Pian, Xumin, Kim, Sung-Chan, Nam, Do-Hyun, Choi, Yun-Jaie, Kim, Hyunggee
Format: Artigo
Langue:Inglês
Publié: Korea Society for Molecular and Cellular Biology 2011
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906874/
https://ncbi.nlm.nih.gov/pubmed/21193962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-011-0008-8
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