Intraperitoneal prophylaxis with CpG oligodeoxynucleotides protects neutropenic mice against intracerebral Escherichia coli K1 infection

BACKGROUND: Prophylaxis with unmethylated cytosine phosphate guanidine (CpG) oligodeoxynucleotides (ODN) protects against several systemic experimental infections. Escherichia coli is a major cause of Gram-negative neonatal bacterial meningitis and also causes meningitis and meningoencephalitis in o...

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Detalhes bibliográficos
Main Authors: Ribes, Sandra, Meister, Tanja, Ott, Martina, Redlich, Sandra, Janova, Hana, Hanisch, Uwe-Karsten, Nessler, Stefan, Nau, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906862/
https://ncbi.nlm.nih.gov/pubmed/24456653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-14
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