B Cell-specific Deficiencies in mTOR Limit Humoral Immune Responses()

Generation of high-affinity antibodies in response to antigens/infectious agents is essential for developing long-lasting immune responses. B cell maturation and antibody responses to antigen stimulation require immunoglobulin (Ig) somatic hypermutation (SHM) and class-switch recombination (CSR) for...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Shuling, Pruitt, Margaret, Tran, Dena, Bois, Wendy Du, Zhang, Ke, Patel, Rushi, Hoover, Shelley, Simpson, R. Mark, Simmons, John, Gary, Joy, Snapper, Clifford M., Casellas, Rafael, Mock, Beverly A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906844/
https://ncbi.nlm.nih.gov/pubmed/23858034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201767
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