Altered steady-state ratio of type I/III procollagen mRNAs correlates with selectively increased type I procollagen biosynthesis in cultured keloid fibroblasts.

Regulation of collagen gene expression was studied in fibroblast cultures established from patients with keloids, fibrotic lesions of the skin. In selected keloid fibroblast cultures, an overproduction of type I procollagen was observed. This increase was accompanied by a parallel increase in type I...

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Autori principali: Uitto, J, Perejda, A J, Abergel, R P, Chu, M L, Ramirez, F
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1985
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC390668/
https://ncbi.nlm.nih.gov/pubmed/3862108
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