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Scleroderma: INCREASED BIOSYNTHESIS OF TRIPLE-HELICAL TYPE I AND TYPE III PROCOLLAGENS ASSOCIATED WITH UNALTERED EXPRESSION OF COLLAGENASE BY SKIN FIBROBLASTS IN CULTURE

To assess potential abnormalities in collagen metabolism in systemic scleroderma, skin fibroblast lines from patients with this disease were established and compared to control cell lines derived from healthy subjects. For studies on the biosynthesis of procollagen, the cells were incubated with [(1...

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Detalles Bibliográficos
Main Authors: Uitto, Jouni, Bauer, Eugene A., Eisen, Arthur Z.
Formato: Artigo
Idioma:Inglês
Publicado: 1979
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC372200/
https://ncbi.nlm.nih.gov/pubmed/90059
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