Modulation of procollagen gene expression by retinoids. Inhibition of collagen production by retinoic acid accompanied by reduced type I procollagen messenger ribonucleic acid levels in human skin fibroblast cultures.

Recent clinical observations have suggested that retinoids, which are in frequent use in dermatology, can affect the connective tissue metabolism in skin and other tissues. In this study, we examined the effects of several retinoids on the metabolism of collagen by human skin fibroblasts in culture....

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Detalhes bibliográficos
Main Authors: Oikarinen, H, Oikarinen, A I, Tan, E M, Abergel, R P, Meeker, C A, Chu, M L, Prockop, D J, Uitto, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC425494/
https://ncbi.nlm.nih.gov/pubmed/2987306
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