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Association of Insulin-Like Growth Factor 2 with the Insulin-Linked Polymorphic Region in Cultured Fetal Thymus Cells

The Insulin-Linked Polymorphic Region (ILPR) is a regulatory sequence in the promoter region upstream of the human insulin gene and is widely recognized as a locus of type 1 diabetes susceptibility. Polymorphism of the ILPR sequence can affect expression of both insulin and the adjacent insulin-like...

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Autors principals: Wang, Yuexi, Zhang, Huiping, Ligon, Lee A., McGown, Linda B.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906629/
https://ncbi.nlm.nih.gov/pubmed/19588890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900958x
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