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A Genome-Inspired DNA Ligand for Affinity Capture of Insulin and Insulin-like Growth Factor-2
The insulin-linked polymorphic region (ILPR) of the human insulin gene contains tandem repeats of similar G-rich sequences, some of which form intramolecular G-quadruplex structures in vitro. Previous work showed affinity binding of insulin to an intramolecular G-quadruplex formed by ILPR variant a....
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774777/ https://ncbi.nlm.nih.gov/pubmed/19391177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jssc.200900060 |
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