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Mass Spectrometric Determination of ILPR G-quadruplex Binding Sites in Insulin and IGF-2
The insulin-linked polymorphic region (ILPR) of the human insulin gene promoter region forms G-quadruplex structures in vitro. Previous studies show that insulin and insulin-like growth factor-2 (IGF-2) exhibit high affinity binding in vitro to 2-repeat sequences of ILPR variants a and h, but neglig...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2763926/ https://ncbi.nlm.nih.gov/pubmed/19747845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2009.08.002 |
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