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Oxidative stress induced by HIV-1 reverse transcriptase modulates the enzyme’s performance in gene immunization
HIV-1 infection induces chronic oxidative stress. The resultant neurotoxicity has been associated with Tat protein. Here, we for the first time describe the induction of oxidative stress by another HIV-1 protein, reverse transcriptase (RT). Expression of HIV-1 RT in human embryonic kidney cells gene...
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| Autors principals: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3906395/ https://ncbi.nlm.nih.gov/pubmed/23881028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.25813 |
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