Oxidative stress induced by HIV-1 reverse transcriptase modulates the enzyme’s performance in gene immunization

HIV-1 infection induces chronic oxidative stress. The resultant neurotoxicity has been associated with Tat protein. Here, we for the first time describe the induction of oxidative stress by another HIV-1 protein, reverse transcriptase (RT). Expression of HIV-1 RT in human embryonic kidney cells gene...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Isaguliants, Maria, Smirnova, Olga, Ivanov, Alexander V., Kilpelainen, Athina, Kuzmenko, Yulia, Petkov, Stefan, Latanova, Anastasia, Krotova, Olga, Engström, Gunnel, Karpov, Vadim, Kochetkov, Sergey, Wahren, Britta, Starodubova, Elizaveta
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Landes Bioscience 2013
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906395/
https://ncbi.nlm.nih.gov/pubmed/23881028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.25813
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