GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation

The amino acid Glutamine is converted into Glutamate by a deamidation reaction catalyzed by the enzyme Glutaminase (GLS). Two isoforms of this enzyme have been described, and the GLS2 isoform is regulated by the tumor suppressor gene p53. Here, we show that the p53 family member TAp73 also drives th...

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Hlavní autoři: Velletri, Tania, Romeo, Francesco, Tucci, Paola, Peschiaroli, Angelo, Annicchiarico-Petruzzelli, Margherita, Niklison-Chirou, Maria Victoria, Amelio, Ivano, Knight, Richard A, Mak, Tak W, Melino, Gerry, Agostini, Massimiliano
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906342/
https://ncbi.nlm.nih.gov/pubmed/24121663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26771
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