GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation

The amino acid Glutamine is converted into Glutamate by a deamidation reaction catalyzed by the enzyme Glutaminase (GLS). Two isoforms of this enzyme have been described, and the GLS2 isoform is regulated by the tumor suppressor gene p53. Here, we show that the p53 family member TAp73 also drives th...

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Detalhes bibliográficos
Main Authors: Velletri, Tania, Romeo, Francesco, Tucci, Paola, Peschiaroli, Angelo, Annicchiarico-Petruzzelli, Margherita, Niklison-Chirou, Maria Victoria, Amelio, Ivano, Knight, Richard A, Mak, Tak W, Melino, Gerry, Agostini, Massimiliano
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906342/
https://ncbi.nlm.nih.gov/pubmed/24121663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26771
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