TAp73 transcriptionally represses BNIP3 expression

TAp73 is a tumor suppressor transcriptional factor, belonging to p53 family. Alteration of TAp73 in tumors might lead to reduced DNA damage response, cell cycle arrest and apoptosis. Carcinogen-induced TAp73(−/−) tumors display also increased angiogenesis, associated to hyperactivition of hypoxia in...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Petrova, Varvara, Mancini, Mara, Agostini, Massimiliano, Knight, Richard A, Annicchiarico-Petruzzelli, Margherita, Barlev, Nikolai A, Melino, Gerry, Amelio, Ivano
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612661/
https://ncbi.nlm.nih.gov/pubmed/25950386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1044178
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