Expression of antibodies using single open reading frame (sORF) vector design: Demonstration of manufacturing feasibility

Efficient production of large quantities of therapeutic antibodies is becoming a major goal of the pharmaceutical industry. We developed a proprietary expression system using a polyprotein precursor-based approach to antibody expression in mammalian cells. In this approach, the coding regions for he...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Gion, Wendy R., Davis-Taber, Rachel A., Regier, Dean A., Fung, Emma, Medina, Limary, Santora, Ling C., Bose, Sahana, Ivanov, Alexander V., Perilli-Palmer, Barbara A., Chumsae, Chris M., Matuck, Joseph G., Kunes, Yune Z., Carson, Gerald R.
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906313/
https://ncbi.nlm.nih.gov/pubmed/23774760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.25161
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items