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A Human Short Open Reading Frame (sORF)-encoded Polypeptide That Stimulates DNA End Joining

The recent discovery of numerous human short open reading frame (sORF)-encoded polypeptides (SEPs) has raised important questions about the functional roles of these molecules in cells. Here, we show that a 69-amino acid SEP, MRI-2, physically interacts with the Ku heterodimer to stimulate DNA doubl...

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Autori principali: Slavoff, Sarah A., Heo, Jinho, Budnik, Bogdan A., Hanakahi, Leslyn A., Saghatelian, Alan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036235/
https://ncbi.nlm.nih.gov/pubmed/24610814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C113.533968
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