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Expression of antibodies using single open reading frame (sORF) vector design: Demonstration of manufacturing feasibility
Efficient production of large quantities of therapeutic antibodies is becoming a major goal of the pharmaceutical industry. We developed a proprietary expression system using a polyprotein precursor-based approach to antibody expression in mammalian cells. In this approach, the coding regions for he...
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| Hlavní autoři: | , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3906313/ https://ncbi.nlm.nih.gov/pubmed/23774760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.25161 |
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