Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets

We have previously shown that peculiar metabolic features of cell adaptation and survival in hypoxia imply growth restriction points that are typical of embryonic stem cells and disappear with differentiation. Here we provide evidence that such restrictions can be exploited as specific antiblastic t...

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Detaylı Bibliyografya
Asıl Yazarlar: Cipolleschi, Maria Grazia, Marzi, Ilaria, Santini, Roberta, Fredducci, David, Vinci, Maria Cristina, D’Amico, Massimo, Rovida, Elisabetta, Stivarou, Theodora, Torre, Eugenio, Dello Sbarba, Persio, Stecca, Barbara, Olivotto, Massimo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2014
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906243/
https://ncbi.nlm.nih.gov/pubmed/24200964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27031
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