Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets

We have previously shown that peculiar metabolic features of cell adaptation and survival in hypoxia imply growth restriction points that are typical of embryonic stem cells and disappear with differentiation. Here we provide evidence that such restrictions can be exploited as specific antiblastic t...

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Detalhes bibliográficos
Main Authors: Cipolleschi, Maria Grazia, Marzi, Ilaria, Santini, Roberta, Fredducci, David, Vinci, Maria Cristina, D’Amico, Massimo, Rovida, Elisabetta, Stivarou, Theodora, Torre, Eugenio, Dello Sbarba, Persio, Stecca, Barbara, Olivotto, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906243/
https://ncbi.nlm.nih.gov/pubmed/24200964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27031
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