Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets

We have previously shown that peculiar metabolic features of cell adaptation and survival in hypoxia imply growth restriction points that are typical of embryonic stem cells and disappear with differentiation. Here we provide evidence that such restrictions can be exploited as specific antiblastic t...

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Autors principals: Cipolleschi, Maria Grazia, Marzi, Ilaria, Santini, Roberta, Fredducci, David, Vinci, Maria Cristina, D’Amico, Massimo, Rovida, Elisabetta, Stivarou, Theodora, Torre, Eugenio, Dello Sbarba, Persio, Stecca, Barbara, Olivotto, Massimo
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906243/
https://ncbi.nlm.nih.gov/pubmed/24200964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27031
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