Frozen Cord Blood Hematopoietic Stem Cells Differentiate into Higher Numbers of Functional Natural Killer Cells In Vitro than Mobilized Hematopoietic Stem Cells or Freshly Isolated Cord Blood Hematopoietic Stem Cells

Adoptive natural killer (NK) cell therapy relies on the acquisition of large numbers of NK cells that are cytotoxic but not exhausted. NK cell differentiation from hematopoietic stem cells (HSC) has become an alluring option for NK cell therapy, with umbilical cord blood (UCB) and mobilized peripher...

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Main Authors: Luevano, Martha, Domogala, Anna, Blundell, Michael, Jackson, Nicola, Pedroza-Pacheco, Isabela, Derniame, Sophie, Escobedo-Cousin, Michelle, Querol, Sergio, Thrasher, Adrian, Madrigal, Alejandro, Saudemont, Aurore
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906137/
https://ncbi.nlm.nih.gov/pubmed/24489840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087086
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