Natural Killer Cells Improve Hematopoietic Stem Cell Engraftment by Increasing Stem Cell Clonogenicity In Vitro and in a Humanized Mouse Model

Cord blood (CB) is increasingly used as a source of hematopoietic stem cells (HSC) for transplantation. Low incidence and severity of graft-versus-host disease (GvHD) and a robust graft-versus-leukemia (GvL) effect are observed following CB transplantation (CBT). However, its main disadvantages are...

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Veröffentlicht in:PLoS One
Hauptverfasser: Escobedo-Cousin, Michelle, Jackson, Nicola, Laza-Briviesca, Raquel, Ariza-McNaughton, Linda, Luevano, Martha, Derniame, Sophie, Querol, Sergio, Blundell, Michael, Thrasher, Adrian, Soria, Bernat, Cooper, Nichola, Bonnet, Dominique, Madrigal, Alejandro, Saudemont, Aurore
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605799/
https://ncbi.nlm.nih.gov/pubmed/26465138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138623
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