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Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation

Graft versus Host Disease (GvHD) remains one of the main complications after hematopoietic stem cell transplantation (HSCT). Due to their ability to suppress effector cells, regulatory T cells (Tregs) have been proposed as a cellular therapy to prevent GvHD, however they also inhibit the functions o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Pedroza-Pacheco, Isabela, Shah, Divya, Domogala, Anna, Luevano, Martha, Blundell, Michael, Jackson, Nicola, Thrasher, Adrian, Madrigal, Alejandro, Saudemont, Aurore
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768165/
https://ncbi.nlm.nih.gov/pubmed/26915707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22097
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