Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation

Graft versus Host Disease (GvHD) remains one of the main complications after hematopoietic stem cell transplantation (HSCT). Due to their ability to suppress effector cells, regulatory T cells (Tregs) have been proposed as a cellular therapy to prevent GvHD, however they also inhibit the functions o...

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Udgivet i:Sci Rep
Main Authors: Pedroza-Pacheco, Isabela, Shah, Divya, Domogala, Anna, Luevano, Martha, Blundell, Michael, Jackson, Nicola, Thrasher, Adrian, Madrigal, Alejandro, Saudemont, Aurore
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768165/
https://ncbi.nlm.nih.gov/pubmed/26915707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22097
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