Inducible, Dose-Adjustable and Time-Restricted Reconstitution of Stat1 Deficiency In Vivo

Signal transducer and activator of transcription (STAT) 1 is a key player in interferon (IFN) signaling, essential in mediating host defense against viruses and other pathogens. STAT1 levels are tightly regulated and loss- or gain-of-function mutations in mice and men lead to severe diseases. We hav...

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Detalhes bibliográficos
Main Authors: Leitner, Nicole R., Lassnig, Caroline, Rom, Rita, Heider, Susanne, Bago-Horvath, Zsuzsanna, Eferl, Robert, Müller, Simone, Kolbe, Thomas, Kenner, Lukas, Rülicke, Thomas, Strobl, Birgit, Müller, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906053/
https://ncbi.nlm.nih.gov/pubmed/24489749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086608
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